Whitepapers

This whitepaper explores why sterile compounding accuracy is inherently limited by cumulative tolerances in tools, medications, and manual handling, and explains how gravimetry and automation can realistically reduce variability. Rather than promising perfection, it positions automation as a transparent, reproducible, and pharmacologically sound improvement over traditional manual practice

This whitepaper explains how mechanical forces in a 50 mL polypropylene syringe such as pressure changes, material deformation, friction, and cavitation, cause dosing deviations during drawing and dispensing. It shows why syringes are not precision instruments and how gravimetric control and system design can mitigate variability and improve reproducibility in pharmacy compounding.

This whitepaper explains how gravimetric weighing is applied in The Compounder, clarifying how measurements are generated, certified, and interpreted under MID and OIML standards. It outlines the meaning of e- and d-values, sources of permissible deviation, and how volume and total weight influence accuracy expectations in daily hospital pharmacy practice.

This whitepaper explains how the EU Measuring Instruments Directive (MID) applies to automated compounding systems that perform gravimetric weighing. It clarifies why MID certification is a system-level requirement, how CE + M marking provides legally defined metrological assurance, and why reliance on non-MID systems increases regulatory, evidentiary, and professional risk for pharmacists and healthcare institutions.